Nguefack-Tsague, Georges and Zucchini, Walter (2011): Modeling hierarchical relationships in epidemiological studies: a Bayesian networks approach.
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Hierarchical relationships between risk factors are seldom taken into account in epidemiological studies though some authors stressed the importance of doing so, and proposed a conceptual framework in which each level of the hierarchy is modeled separately. The objective of this paper was to implement a simple version of their framework, and to propose an alternative procedure based on a Bayesian Network (BN). These approaches were illustrated in modeling the risk of diarrhea infection for 2740 children aged 0 to 59 months in Cameroon. The authors implemented a (naïve) logistic regression, a step-level logistic regression and also a BN. While the first approach is inadequate, the two others approaches both account for the hierarchical structure but to different estimates and interpretations. BN implementation showed that a child in a family in the poorest group has respectively 89%, 40% and 18% probabilities of having poor sanitation, being malnourished and having diarrhea. An advantage of the latter approach is that it enables one to determine the probability that a risk factor (and/or the outcome) is in a given state, given the states of the others. Although the BN considered here is very simple, the method can deal with more complicated models.
|Item Type:||MPRA Paper|
|Original Title:||Modeling hierarchical relationships in epidemiological studies: a Bayesian networks approach|
|Keywords:||Bayesian networks; hierarchical model; diarrhea infection; disease determinants; logistic regression|
|Subjects:||I - Health, Education, and Welfare > I1 - Health > I12 - Health Production
C - Mathematical and Quantitative Methods > C4 - Econometric and Statistical Methods: Special Topics > C45 - Neural Networks and Related Topics
C - Mathematical and Quantitative Methods > C1 - Econometric and Statistical Methods and Methodology: General > C11 - Bayesian Analysis: General
|Depositing User:||Georges Nguefack-Tsague|
|Date Deposited:||19. Jan 2011 20:47|
|Last Modified:||14. Feb 2013 12:55|
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