Brazier, J (2001): Quality of life evidence for patients with Alzheimer’s disease: use of existing quality of life evidence from the ADENA trials to estimate the utility impact of Exelon®.
Download (254kB) | Preview
This paper utilises the Mini-Mental State Examination (MMSE) score of patients with Alzheimer’s disease to establish a relationship between disease progression and quality of life measures, and the author also compares his results to findings from the literature review about Alzheimer’s patient utility.
|Item Type:||MPRA Paper|
|Original Title:||Quality of life evidence for patients with Alzheimer’s disease: use of existing quality of life evidence from the ADENA trials to estimate the utility impact of Exelon®|
|Keywords:||Alzheimer's disease; quality of life|
|Subjects:||I - Health, Education, and Welfare > I3 - Welfare and Poverty > I31 - General Welfare
I - Health, Education, and Welfare > I1 - Health > I19 - Other
|Depositing User:||Sarah McEvoy|
|Date Deposited:||24. Mar 2011 21:05|
|Last Modified:||16. Feb 2013 08:29|
Feeny DH, Torrance GW, Furlong WJ (1996). Health Utilities Index. Ch 26 in Quality of Life in Clinical Trials 2nd Edition, edited by Spilker B. Lippincott-Raven Publishers, Philadelphia.
Furlong W, Feeny D et al (1998). Multiplicative multi-attribute utility function for the Health Utilities Index Mark 3 (HUI 3) system: a technical report. McMaster University Centre for Health Economics and Policy Analysis Working Paper 98-11.
Novartis (1997). Integrated summary of effectiveness. Project SDZ ENA 713
Neumann PJ, Hermann RC, Weinstein MC (1998). Measuring QALYs in dementia. Ch 3.3 in Health Economics of Dementia, edited by Wimo A, Jonsson B, Karlsson G, Winblad B. John Wiley and Sons Ltd.
Neumann PJ, Sandberg EA et al (1999). A comparison of HUI 2 and HUI 3 utility scores in Alzheimer’s disease. Working paper.
Wessex Institute (1998). Rivastigmine (Exelon) in the treatment of senile dementia of the Alzheimer type (SDAT). Development and Evaluation Committee Report no 89.
Neumann PJ et al (2000). A comparison of HU12 and HU13 utility scores in Alzheimer's disease. Medical Decision Making 20:413-22.
Neumann PJ, Kuntz KM, Leon J, Araki SS, et al (1999). Health utilities in Alzheimer's disease: a cross-sectional study of patients and caregivers. Medical Care 37(1):27-32.
Leon J, Neumann PJ, Hermann RC, Hsu M, Cummings JL, Doraiswamy PM, Marin D (2000). Health-related quality-of-life and service utilization in Alzheimer's disease: a cross-sectional study. American Journal of Alzheimer's Disease & Other Dementias 15(2):94-108.