Tsuchiya, A and Brazier, J and McColl, E and Parkin, D (2002): Deriving preference-based single indices from non-preference based condition-specific instruments: converting AQLQ into EQ5D indices.
Download (262kB) | Preview
Suppose that one has a clinical dataset with only non-preference-based QOL data, and that one nevertheless would like to perform a cost/QALY analysis. This study reports on some efforts to establish a “mapping” relationship between AQLQ (a non-preference-based QOL instrument for asthma) and EQ5D (a preference-based generic instrument). Various methods are described in terms of associated assumptions regarding the measurement properties of the instruments. This is followed by empirical mapping, based on regressing EQ5D on AQLQ. Six main regression models and two supplementary models are identified, and the regressions carried out. Performance of each model is explored in terms of goodness of fit between observed and predicted values, and of robustness of predictions on external data. The results show that it is possible to predict mean EQ5D indices given AQLQ data. The general implications for methods of mapping non-preference-based instruments onto preference-based measures are discussed.
|Item Type:||MPRA Paper|
|Original Title:||Deriving preference-based single indices from non-preference based condition-specific instruments: converting AQLQ into EQ5D indices|
|Keywords:||EQ5D; AQLQ; mapping|
|Subjects:||I - Health, Education, and Welfare > I3 - Welfare and Poverty > I31 - General Welfare
I - Health, Education, and Welfare > I1 - Health > I19 - Other
|Depositing User:||Sarah McEvoy|
|Date Deposited:||24. Mar 2011 21:48|
|Last Modified:||18. Feb 2013 00:18|
Juniper EF, Guyatt GH, Ferrie PJ, Griffith LE (1993). Measuring quality of life in asthma. American Review of Respiratory Disease 147:832-8.
Juniper EF, Buist AS, Cox FM, Ferrie PJ, King DR (1999). Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest 115(5):1265-70.
Brooks R for the EuroQol Group (1996). EuroQol: The current state of play. Health Policy 37:53-72.
Dolan P (1997). Modelling valuation for Euroqol health states. Medical Care 35:351-63.
The MVH Group (1995). The measurement and valuation of health: final report on the modelling of valuation tariffs. Centre for Health Economics, University of York.
Revicki DA, Leicy NK, Brennan-Diemer F, Sorensen S, Togias A (1998). Integrating patient preferences into health outcomes assessment: the multiattribute asthma symptom utility index. Chest 114:998-1007.
McKenzie L, Carins J, Osman L (2001). Symptom-based outcome measures for asthma: the use of discrete choice methods to assess patient preferences. Health Policy 57:193-204.
Chancellor J, Coyle D, Drummond M (1997). Constructing health state preference values from descriptive quality of life outcomes: mission impossible? Quality of Life Research 6:159-168.
Brazier JE, Usherwood TP, Harper R, Jones NMB, Thomas K (1998). Deriving a preference based single index measure for health from the SF-36. Journal of Clinical Epidemiology 51(11):1115-29.
Brazier J, Roberts J, Deverill M (2002). The estimation of a utility based algorithm from the SF-36 Health Survey. Journal of Health Economics.
Coast J (1992). Reprocessing data to form QALYs. British Medical Journal 305(6845):87-90.
Eccles M, Grimshaw J, Steen N, Parkin D, Purves I, McColl E, et al (2000). The design and analysis of a randomized controlled trial to evaluate computerized decision support in primary care: the COGENT study. Family Practice 17(2):180-6.