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The 2 x 2 x 2 case in causality, of an effect, a cause and a confounder. A cross-over’s guide to the 2 x 2 x 2 contingency table

Colignatus, Thomas (2007): The 2 x 2 x 2 case in causality, of an effect, a cause and a confounder. A cross-over’s guide to the 2 x 2 x 2 contingency table. Unpublished.

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Abstract

Basic causality is that a cause is present or absent and that the effect follows with a success or not. This happy state of affairs becomes opaque when there is a third variable that can be present or absent and that might be a seeming cause. The 2 x 2 x 2 layout deserves the standard name of the ETC contingency table, with variables Effect, Truth and Confounding and values {S, -S}, {C, -C}, {F, -F}. Assuming the truth we can find the impact of the cause from when the confounder is absent. The 8 cells in the crosstable can be fully parameterized and the conditions for a proper cause can be formulated, with the parameters interpretable as regression coefficients. Requiring conditional independence would be too strong since it neglects some causal processes. The Simpson paradox will not occur if logical consistency is required rather than conditional independence. The paper gives a taxonomy of issues of confounding, a parameterization by risk or safety, and develops the various cases of dependence and (conditional) independence. The paper is supported by software that allows variations. The paper has been written by an econometrician used to structural equations models but visiting epidemiology hoping to use those techniques in experimental economics.

Item Type:MPRA Paper
Institution:Thomas Cool Consultancy & Econometrics
Language:English
Keywords:Experimental economics; causality; cause and effect; confounding; contingency table; Simpson paradox; conditional independence; risk; safety; epidemiology; correlation; regression; Cornfield’s condition; inference
Subjects:C - Mathematical and Quantitative Methods > C1 - Econometric and Statistical Methods: General > C10 - General
ID Code:3351
Deposited By:Thomas Colignatus
Deposited On:29. May 2007
Last Modified:07. Nov 2007 03:08
References:

Colignatus is the name of Thomas Cool in science.

Cool, Th. (1999, 2001), “The Economics Pack, Applications for Mathematica”, http://www.dataweb.nl/~cool, ISBN 90-804774-1-9, JEL-99-0820

Colignatus, Th. (2007d), “Correlation and regression in contingency tables. A measure of association or correlation in nominal data (contingency tables), using determinants", http://mpra.ub.uni-muenchen.de/3226/01/MPRA_paper_3226.pdf, Retrieved from source

Colignatus, Th. (2007e), “Elementary statistics and causality”, work in progress, http://www.dataweb.nl/~cool/Papers/ESAC/Index.html

Fisher, R.A. (1958a), “Lung Cancer and Cigarettes? Letter to the editor”, Nature, vol. 182, p. 108, 12 July 1958 [Collected Papers 275], see Lee (2007), http://www.york.ac.uk/depts/maths/histstat/fisher275.pdf, Retrieved from source

Fisher, R.A. (1958b), “Cancer and Smoking? Letter to the editor”, Nature, vol. 182, p. 596, 30 August 1958 [Collected Papers 276], see Lee (2007), http://www.york.ac.uk/depts/maths/histstat/fisher276.pdf, Retrieved from source

Kleinbaum, D.G., K.M. Sullivan and N.D. Barker (2003), “ActivEpi Companion texbook”, Springer

Lee, P.M. (2007), “Life and Work of Statisticians”, http://www.york.ac.uk/depts/maths/histstat/lifework.htm, Revised 24 April 2007

Pearl, J. (1998), “Why there is no statistical test for confounding, why many think there is, and why they are almost right”, UCLA Cognitive Systems Laboratory, Technical Report (R-256), January 1998

Pearl, J. (2000), “Causality. Models, reasoning and inference”, Cambridge

Saari, D.G. (2001), “Decisions and elections”, Cambridge

Schield, M. (1999, 2003), “Simpson’s paradox and Cornfield’s conditions”, Augsburg College ASA-JSM, http://web.augsburg.edu/~schield/MiloPapers/99ASA.pdf, 07/23/03 Updated, Retrieved from source

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