Ramlogan, Ronnie and Consoli, Davide (2008): Knowledge, understanding and the dynamics of medical innovation. Forthcoming in: European Journal of Economic and Social Systems No. 20 : pp. 231-249.
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This paper investigates the processes by which scientific knowledge is created and legitimized. It focuses on scientific developments in a branch of medicine and explores the pathways through which the growth of knowledge enables advances in medical science and in clinical practice. This work draws conceptually on evolutionary approaches to technological change. The empirical part presents a longitudinal analysis of a database of scientific publications in the field of ophthalmology over a period of 50 years. Such an exercise allows us to identify pathways of shared understanding on a disease area, and to map out distinctive trajectories followed by the ophthalmology research community. The paper also contributes to general understanding of the innovation process by supporting the notion that knowledge coordination is a distributed process that cuts across and connects complementary areas of expertise.
|Item Type:||MPRA Paper|
|Original Title:||Knowledge, understanding and the dynamics of medical innovation|
|Subjects:||O - Economic Development, Technological Change, and Growth > O3 - Technological Change; Research and Development; Intellectual Property Rights > O33 - Technological Change: Choices and Consequences; Diffusion Processes
D - Microeconomics > D8 - Information, Knowledge, and Uncertainty > D83 - Search; Learning; Information and Knowledge; Communication; Belief
O - Economic Development, Technological Change, and Growth > O3 - Technological Change; Research and Development; Intellectual Property Rights > O31 - Innovation and Invention: Processes and Incentives
|Depositing User:||Davide Consoli|
|Date Deposited:||12. Jun 2008 16:10|
|Last Modified:||12. Feb 2013 11:01|
Airaksinen PJ, Tuulonen A. (1984) “Early glaucoma changes in patients with and without an optic disc haemorrhage”, Acta Ophthalmolica (Copenh) 62(2): 197-202.
Amsterdamska, O. (1987) “Medical and Biological Constraints: Early Research on Variation in Bacteriology”, Social Studies of Science 17(44): 657-687.
Antonelli, C. (2001) The microeconomics of technological systems. Oxford University Press: Oxford.
Batagelj, V. (2002) “Efficient Algorithms for Citation Network Analysis”, Working Paper, Department of Theoretical Computer Science, University of Ljubljana.
Begg I.S., Drance S.M. and Sweeney V.P. (1971) “Ischaemic optic neuropathy in chronic simple glaucoma”, British Journal of Ophthalmology 55(2): 73-90.
Blume, S. (1992) Insight and Industry: On the Dynamics of Technological Change in Medicine. MIT Press: Boston.
Consoli, D., A. McMeekin, R. Ramlogan, A. Mina, G. Tampubolon and J.S. Metcalfe (2005) “Progress in Medicine: Structure and Evolution of Know-how for the treatment of Glaucoma”, CRIC Discussion Paper Series No. 72, University of Manchester.
Consoli, D. and A. Mina (2007) “Medicine and change: An evolutionary perspective on the dynamics of Health Innovation Systems”, Presented to the European Meeting of Applied Evolutionary Economics (EMAEE), Manchester Metropolitan University.
Consoli, D. and R. Ramlogan (2008) “Out of sight: problem sequences and epistemic boundaries of medical know-how on glaucoma”, Journal of Evolutionary Economics 18(1): 31-56.
David, P.A. (2001) “Path Dependence, its Critics and the Quest for Historical Economics”. In: P. Garrouste and S. Ioannides (eds.) Evolution and Path Dependence in Economic Ideas: Past and Present. Cheltenham: Edward Elgar.
Dosi, G. (1988) “The nature of the innovative process”. In: Dosi, G., Freeman, C., Nelson, R., Silverberg, G., Soete, L. (Eds), Technical Change and Economic Theory, Pinter, London.
Drance S.M. and Begg I.S. (1970) “Sector haemorrhage: a probable acute ischaemic disc change in chronic simple glaucoma”, Canadian Journal of Ophthalmology 5(2): 137-141.
Duke-Elder, S. (1959) System of Ophthalmology, Henry Kimpton, London.
Feldman, F., Sweeney, V.P. and Drance, S.M. (1969) “Cerebro-vascular studies in chronic simple glaucoma”, Canadian Journal of Ophthalmology 4(4): 358-64.
Fontana, R., Nuvolari A. and B. Verspagen (2007) “Mapping Technological Trajectories as Patent Citation Networks. An Application to Data Communication Standards”, forthcoming in Economics of Innovation and New Technology.
Garfield, E. (1972) “Citation analysis as a tool in journal evaluation”, Science 178: 471–479.
Gelijns, A.C. and N. Rosenberg (1994) “The Dynamics of Technological Change in Medicine”, Health Affairs 13(3): 28-46.
Gelijns A.C., J. Zivin, and R.R. Nelson (2001) “Uncertainty and Technological Change in Medicine”, Journal of Health Politics, Policy and Law 26: 913-924.
Gibbons, M., C. Limoges, H. Nowotny, S. Schwartzman, P. Scott and M. Trow (1994) The new production of knowledge, London: Sage.
Høvding, G. and Aasved, H. (1986) “Prognostic factors in the development of manifest open angle glaucoma. A long-term follow-up study of hypertensive and normotensive eyes”, Acta Ophthalmologica (Copenh) 64(6): 601-608.
Hummon, N.P. and P. Doreian (1989) “Connectivity in a citation network: the development of DNA theory”, Social Networks 11: 39-63.
Kogut, B. and U. Zander (2003) “Knowledge of firm and the evolutionary theory of the multinational corporation”, Journal of International Business Studies 34 (6): 516–529.
Langlois, R.N. and D.A. Savage (2001) “Standards, Modularity, and Innovation: the case of Medical Practice”. In: R. Garud and P. Karnøe (eds.) Path Dependence and Path Creation. Hillsdale, NJ: Lawrence Erlbaum.
Leydesdorff, L, (1994) “The Generation of Aggregated Journal-Journal Citation Maps on the basis of The Cd-Rom Version of the Science Citation Index”, Scientometrics 31(1): 59-84.
Leydesdorff, L, (2003) “Can Networks of Journal-Journal Citations be Used as Indicators of Change in the Social Sciences ?”, Journal Of Documentation, 59(1): 84-104.
Leydesdorff, L. and É., Gauthier (1996) “The Evaluation of National Performance in Selected Priority Areas using Scientometric Methods”, Research Policy 25(3): 431-50.
Loasby, B.J. (1991) Equilibrium and Evolution: an Exploration of Connecting Principles in Economics. Manchester: Manchester University Press.
Loasby, B.J. (1998) “The organization of capabilities”, Journal of Economic Behaviour and Organization 35: 139-160.
Loasby, B.J. (1999) Knowledge Institutions and Evolution in Economics. The Graz Schumpeter Lectures. London and New York: Routledge.
Loasby, B.J. (2001) “Time, knowledge and evolutionary dynamics: why connections matter”, Journal of Evolutionary Economics, 11 (4), 393-412.
Metcalfe, J.S. (2001) “Institutions and Progress”, Industrial and Corporate Change, 10(3): 561-586.
Metcalfe, J.S. and R. Ramlogan (2005) “Limits to the Economy of Knowledge and Knowledge of the Economy”, Futures 37: 655-674.
Metcalfe, J.S., James, A. and A. Mina (2005) “Emergent Innovation Systems and the Delivery of Clinical Services: the Case of Intra-Ocular Lenses”, Research Policy 34(9): 1283-1304.
Mina, A., R. Ramlogan, G. Tampubolon, and J.S. Metcalfe (2007) “Mapping evolutionary trajectories: applications to the growth and transformation of medical knowledge”, Research Policy 36 (5): 789-806.
Nelson, R.R. (1995) “Recent Evolutionary Theorizing about Economic Change”, Journal of Economic Literature, 33(1): 48-90.
Nelson, R.R. (2002) “Bringing institutions into evolutionary growth theory”, Journal of Evolutionary Economics, 12: 17-28.
Nelson, R.R. (2003) “On the uneven evolution of human know-how”, Research Policy 32: 909-922.
Nelson, R.R. (2005) “Physical and Social Technologies, and their Evolution”, in R.R. Nelson, Technology, Institutions, and Economic Growth. Harvard University Press.
Quigley, H.A. (2004) New paradigms in the mechanisms and management of glaucoma. Eye (The Doyne Lecture). Available online at http://dx.doi.org/10.1038/sj.eye.6701746
Ramlogan, R., A. Mina., G. Tampubolon and J.S. Metcalfe (2007) “Networks of Knowledge: the distributed nature of Medical Innovation”, Scientometrics 70(2): 459-489.
Ray, K., Mukhopadhyay, A. and M. Acharya (2003) “Recent advances in molecular genetics of glaucoma”, Molecular and Cellular Biochemistry 253(1-2): 223-31.
Rosenberg, N. (1974) “Science, Invention and Economic Growth”, The Economic Journal 84 (333), 90-108.
Sarfarazi M. (1997) “Recent advances in molecular genetics of glaucomas”, Human Molecular Genetics 6(10): 1667-77.
Shackle, G.L.S. (1992) Epistemics and Economics. New Brunswick: Transaction Publishers. Originally published in 1972.
Shryock, R.H. (1974) The development of modern medicine: an interpretation of the social and scientific factors involved. Madison: University of Wisconsin Press.
Utterback, J. (1994) Mastering the Dynamics of Innovation. Boston: Harvard Business School Press.
Van den Besselaar, P. & Leydesdorff. L, (1996) “Mapping Change in Scientific Specialties: a Scientometric Reconstruction of the Development of Artificial Intelligence”, Journal of the American Society for Information Science, 47(6): 415-36.
Verspagen, B. (2007), Mapping technological trajectories as patent citations networks. A study on the history of fuel cell research. Advances in Complex Systems. 10: 93-115.
von Hayek, F.A. (1945) “The Use of Knowledge in Society”, American Economic Review, 35: 519-530.
von Hippel, E. (1976) „The Dominant Role of Users in the Scientific Instrument Innovation Process“, Research Policy 5(3): 212-39.
von Hippel, E., 1988, The Sources of Innovation, Oxford University Press
Weisse, A.B. (1991) Medical odysseys: the different and sometimes unexpected pathways to twentieth-century medical discoveries. New Brunswick, N.J.: Rutgers University Press.
Ziman, J.M. (1968) Public Knowledge: The Social Dimension of Science. London, UK: Cambridge University Press. Ziman, J.M. (1978) Reliable Knowledge. Cambridge, UK: Cambridge University Press.