Khazabi, Massoud and Quyen, Nguyen (2010): The Search for New Drugs: A Theory of R&D in the Pharmaceutical Industry.
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The paper formalizes, in a rigorous manner, the concept of information externalities, by modeling R&D activities as the process of searching for a drug to treat a disease, with R&D activities being modeled from the perspective of the theory of optimal search. In conventional models of patent design, only one brand - the brand with the highest quality - is available on the market at any time. Furthermore, demand is completely inelastic: each consumer, regardless of income and regardless of the price of the brand offered on the market, buys exactly one unit of the brand. In this model, which is a dynamic model in continuous time, several differentiated products - the products whose patents are still in force and the products whose patents have expired - are available at any time on the market. Furthermore, the demand for a brand depends on income, its own price, and the prices of the other brands. The analyses of R&D as well as the impact of the cost and the quality of newly discovered drugs on the market are represented under this framework, when the pharmaceutical firms with an active drug discovery program behave strategically in both R&D and in the product market.
|Item Type:||MPRA Paper|
|Original Title:||The Search for New Drugs: A Theory of R&D in the Pharmaceutical Industry|
|Keywords:||R&D, Patent, Spillovers|
|Subjects:||O - Economic Development, Innovation, Technological Change, and Growth > O3 - Innovation ; Research and Development ; Technological Change ; Intellectual Property Rights > O34 - Intellectual Property and Intellectual Capital|
|Depositing User:||Massoud Khazabi|
|Date Deposited:||15 Jun 2012 12:52|
|Last Modified:||24 Jun 2016 14:37|
ARROW, K. J. AND S. CHANG (1982): “Optimal Pricing, Use, and Exploration of Uncertain Resource Stocks,” Journal of Environmental Economics and Management, 9, 1-10.
CAIRNS, R. AND N. V. QUYEN (1998): “Optimal Exploration for and Exploitation of Heterogenous Miniral Deposits,” Journal of Environmental Economics and Management, 35, 164-189.
CHOW, G. C. (1981): Economic Analysis by Control Methods, New York: John Wiley & Sons.
EATON, J. AND S. KHORTUM (2001): “Technology, Trade, and Growth: A Unified Framework,”European Economic Review, 451, 742-755.
GILBERT, R. AND C. SHAPIRO (1990): “Optimal Patent Length and Breadth,” The Rand Journal of Economics, 21, 106-112.
KLEMPERER, P.(1990): “How Broad Should the Scope of Patent be?” The Rand Journal of Economics, 21, 113-130.
MANSFIELD, E. (1961): “Technical Change and the Rate of Imitation,” Econometrica, 29, 741-766.
MANSFIELD, E. (1984): “R&D and Innovation: Some Empirical Findings,” in Zvi Griliches, ed., R&D, Patents and Productivity, Chicago: University of Chicago Press for the National Bureau of Economic Research.
NORDHAUS, W. (1969): Invention, Growth, and Welfare, Cambridge, Massachusetts, MIT Press.
NORDHAUS, W. (1972): “The Optimal Life of the Patent: Reply,” American Economic Review, 62, 428-431.
O’DONOGHUE, TED, S. SCOTCHMER, and J.-F. THISSE (1998): “Patent Breadth, Patent Life, and the Pace of Technological Progress,” Journal of Economics & Management Strategy, Vol. 7, No. 1, 1-32.
PERLMAN, R. H. (2009): “Novel Software Tools for Addressing Chemical Diversity,”Copyright © 1995-2009 Network Science Corporation.
QUYEN, N. V. (1991): “Exhaustible Resources: A Theory of Exploration,” Review of Economic Studies, 58, 777-789.
SCOTCHMER, S. AND J. GREEN (1990): “Novelty and Disclosure in Patent Law,” The Rand Journal of Economics, 21, 131-146.
TAKALO, T. (2001): "On the optimal patent policy," Finnish Economic Papers, Finnish Economic Association, vol. 14(1), pages 33-40.
TANDON, P. (1982): “Optimal patents with compulsory licensing, ”Journal of Political Economy, 90, 470–486.
TOULLY, VÉRONIQUE et al. (2002): “Pharmaceutical Industry: Innovation and Economic Performance: A Study on Behalf of Laboratoires Internationaux de Recherch, 18 pages