Mueller-Langer, Frank (2011): Neglected infectious diseases: are push and pull incentive mechanisms suitable for promoting research?
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Abstract
Infectious diseases are among the main causes of death and disability in developing countries, and they are a major reason for the health disparity between rich and poor countries. One of the reasons for this public health tragedy is a lack of lifesaving essential medicines, which either do not exist or badly need improvements. In this article, we analyse which of the push and pull mechanisms proposed in the recent literature may serve to promote research into neglected infectious diseases. A combination of push programs that subsidise research inputs through direct funding and pull programs that reward research output rather than research input may be the appropriate strategy to stimulate research into neglected diseases. On the one hand, early-stage (basic) research should be supported through push mechanisms, such as research grants or publicly financed research institutions. On the other hand, pull mechanisms, such as prize funds that link reward payments to the health impacts of effective medicines, have the potential to stimulate research into neglected diseases.
Item Type: | MPRA Paper |
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Original Title: | Neglected infectious diseases: are push and pull incentive mechanisms suitable for promoting research? |
Language: | English |
Keywords: | Neglected infectious diseases; Research and Development; push incentive mechanisms; pull incentive mechanisms |
Subjects: | I - Health, Education, and Welfare > I1 - Health > I12 - Health Behavior I - Health, Education, and Welfare > I1 - Health > I18 - Government Policy ; Regulation ; Public Health L - Industrial Organization > L3 - Nonprofit Organizations and Public Enterprise O - Economic Development, Innovation, Technological Change, and Growth > O3 - Innovation ; Research and Development ; Technological Change ; Intellectual Property Rights > O31 - Innovation and Invention: Processes and Incentives |
Item ID: | 40193 |
Depositing User: | Frank Müller-Langer |
Date Deposited: | 20 Jul 2012 18:25 |
Last Modified: | 28 Sep 2019 01:38 |
References: | Acemoglu, D. and J. Linn (2004), ‘Market size in innovation: theory and evidence from the pharmaceutical industry’, Quarterly Journal of Economics, 119(3): 1049-1090. Berndt, E.R., R. Glennerster, M. Kremer, J. Lee, R. Levine, G. Weizsäcker and H.L. Williams (2007), ‘Advance market commitments for vaccines against neglected diseases: estimating costs and effectiveness’, Health Economics, 16(4): 491-511. Buckup, S. (2008), ‘Global public-private partnerships against neglected diseases: building governance structures for effective outcomes’, Health Economics, Policy and Law, 3: 31-50. DiMasi, J.A., R.W. Hansen and H.G. Grabowski (2003), ‘The price of innovation: new estimates of drug development costs’, Journal of Health Economics, 22:151-185. Gallini, N.T. and S. Scotchmer (2002), ‘Intellectual property: when is it the best incentive system?’, in A.B. Jaffe, J. Lerner and S. Stern (Eds), Innovation policy and the economy, Volume 2. Cambridge, MA: MIT Press, 51-77. Glennerster, R. and M. Kremer (2001), ‘A better way to spur medical research and development’, Regulation, 23(2): 34-39. Grabowski, H.G. and J.M. Vernon (2000), ‘The determinants of pharmaceutical research and development expenditures’, Journal of Evolutionary Economics, 10(1/2): 201-215. Hall, B.H. and J. van Reenen (2000), ‘How effective are fiscal incentives for R&D? A review of the evidence’, Research Policy, 29: 449-469. Harhoff, D., F.M. Scherer and K. Vopel (2003), ‘Citations, family size, opposition and the value of patent rights’, Research Policy, 32(8): 1343-1363. Hollis, A. (2007), ‘Drugs for neglected diseases: new incentives for innovation’ in F.A. Sloan and C.R. Hsieh (Eds), Pharmaceutical innovation: incentives, competition, and cost-benefit analysis in international perspective. Cambridge: Cambridge University Press, 75-90. Hollis, A. and P. Pogge (2008), The health impact fund: making new medicines accessible for all, New Haven, CT: Incentives for Global Health. Kettler, H.E. and R. Modi (2001), ‘Building research and development capacity for the prevention and cure of neglected diseases: the case of India’, Bulletin of the World Health Organization, 79(8): 742-747. Kremer, M. (1998), ‘Patent buyouts: a mechanism for encouraging innovation’, Quarterly Journal of Economics, 113(4): 1137-1167. Kremer, M. (2001), ‘Creating markets for new vaccines: part I: rationale’, in A.B. Jaffe, J. Lerner and S. Stern (Eds), Innovation policy and the economy, Volume 1. Cambridge, MA: MIT Press, 35-72. Kremer, M. (2002), ‘Pharmaceuticals and the developing world’, Journal of Economic Perspectives, 16(4): 67-90. Kremer, M. and R. Glennerster (2000), ‘A world bank vaccine commitment’, Brookings Institution Policy Brief, 57: 1-8. Kremer, M. and R. Glennerster (2004), Strong medicine, creating incentives for pharmaceutical research and neglected diseases, New Jersey: Princeton University Press. Kremer, M. and H. Williams (2010), ‘Incentivizing innovation: adding to the tool kit’, in J. Lerner and S. Stern (Eds), Innovation policy and the economy, Volume 10, Chicago, IL: University of Chicago Press, 1-17. Layne-Farrar, A. and K.M. Schmidt (2010), ‘Licensing complementary patents: ‘patent trolls’, market structure, and ‘excessive royalties’’, Berkeley Technology Law Journal, 25: 1121-1144. Lichtenberg, F.R. and J. Waldfogel (2003), Does misery love company? Evidence from pharmaceutical markets before and after the orphan drug act, NBER Working Paper, No. 9750, Washington, D.C.: National Bureau of Economic Research. Liddell, K. (2010), ‘The health impact fund: a critique’, in T. Pogge, M. Rimmer and K. Rubenstein (Eds), Incentives for global public health: patent law and access to essential medicines, Cambridge: Cambridge University Press, 155-180. Love, J. and T. Hubbard (2007) ‘The big idea: prizes to stimulate R&D for new medicines’, Chicago-Kent Law Review, 82(3): 1519-1554. Lybecker, K.M. and R.A. Freeman (2007), ‘Funding pharmaceutical innovation through direct tax credits’, Health Economics, Policy and Law, 2: 267-284. Maurer, S.M. (2005), The right tool(s): designing cost-effective strategies for neglected disease research, Report to WHO Commission on Intellectual Property Rights, Innovation and Public Health. Geneva: WHO. Mrazek, M.F. and E. Mossialos (2003), ‘Stimulating pharmaceutical research and development for neglected diseases,’ Health Policy, 64: 75-88. Pogge, T. (2010), ‘The health impact fund: better pharmaceutical innovations at much lower prices’, in T. Pogge, M. Rimmer and K. Rubenstein (Eds), Incentives for global public health: patent law and access to essential medicines. Cambridge: Cambridge University Press, 135-154. Ricklin, D. and J.D. Lambris (2007), ‘Complement-targeted therapeutics’, Nature Biology, 25(11): 1265-1275. Shulman, S.R. and M. Manocchia (1997), ‘The U.S. orphan drug programme: 1983-1995’, PharmacoEconomics, 12(3): 312-326. Stiglitz, J.E. and A. Jayadev (2010), ‘Medicine for tomorrow: some alternative proposals to promote socially beneficial research and development in pharmaceuticals’, Journal of Generic Medicines, 7(3): 220-221. Trouiller, P., P. Olliaro, E. Torreele, J. Orbinski, R. Laing and N. Ford (2002), ‘Drug development for neglected diseases: a deficient market and a public-health policy failure’, Lancet, 359(9324): 2188-2194. Villa, S., A. Compagni and M.R. Reich (2009) ‘Orphan drug legislation: lessons for neglected tropical diseases’, International Journal of Health Planning and Management, 24(1): 27-42. Webber, D. and M. Kremer (2001), ‘Perspectives on stimulating industrial research and development for neglected infectious diseases’, Bulletin of the World Health Organization, 79(8): 735-741. World Health Organization (2001), World health report 2001. Geneva: World Health Organization. World Health Organization (2005), World malaria report 2005. Geneva: World Health Organization. World Health Organization (2008), The global burden of disease: 2004 update. Geneva: World Health Organization. |
URI: | https://mpra.ub.uni-muenchen.de/id/eprint/40193 |